Download 2011-2012 Basic and Clinical Science Course, Section 12: by Carl D. Regillo MD PDF

By Carl D. Regillo MD

Reports the fundamental anatomy of the retina and diagnostic techniques to retinal sickness. comprises large examinations of issues of the retina and vitreous, together with ailment, irritation, hereditary dystrophies, abnormalities and trauma. Discusses laser remedy and vitreoretinal surgical procedure. final significant revision 2008-2009.

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Additional info for 2011-2012 Basic and Clinical Science Course, Section 12: Retina and Vitreous (Basic & Clinical Science Course)

Example text

The fluorescein remains in the choroid and does not enter the retina. A Figure 2-2 Typical central serous chorioretinopathy. A, The red-free black-a nd-white photograph of t he right macula reveals a w ell-demarcated serous detachment of the sensory retina (arrows). B, Early transit frame of t he angiogram revea ls the pinpoint focus of hyperfluorescence, indicating early fluorescein leakage (arrow) through the RPE, nasal to the foveal avascular zone. C, A late venous phase frame of the angiogram reveals increasing fluorescence from continuing leakage.

0 , A later frame of the angiogram demonstrates pooling of fluorescein in a pigment epithelial detachment. Also note the mild hyperfluorescence caused by generalized stainin g of the serous fluid ben'eath the sensory retina . The RPE outside the fovea typically is mottled and hyperfluorescent. CHAPT ER 2: Diag nostic Approach to Retinal Dise ase. 25 Autofluorescence describes the appearance of fluo rescence fro111 the fundus captured prior to intravenous fluorescein injection. It is seen with structures that naturally fluoresce, such as optic nerve drusen and lipofuscin.

By evaluating differences in retinal volume over time, the clinician can evaluate the efficacy of therapy. Time-domain OCT produces retinal thickness maps from 6 x 6-mm radial scans centered on the fovea, with interpolation between the scan lines, to produce a map of the macula. In contrast, Fourier-domain OCT can image the entire macula due to increased scanning speed and improved accuracy of thick ness and volume measurements; it also offers the capability of improving registration, so imaging the same area from visit to visit is now possible.

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