By John S. Bradley MD, John D. Nelson MD Emeritus, Dr. David W Kimberlin MD FAAP, Dr. John A.D. Leake MD MPH, Dr. Paul E Palumbo MD, Dr. Pablo J Sanchez MD, Dr. Jason Sauberan PharmD, Dr. William J Steinbach
This bestselling and familiar source on pediatric antimicrobial treatment offers quick entry to trustworthy suggestions for therapy of all infectious ailments in children.
For every one ailment, the authors supply a observation to assist well-being care services decide upon the easiest of all antimicrobial offerings. The inquiring general practitioner can instantly hyperlink to the facts for the advice within the publication or cellular model. Drug descriptions hide all antimicrobial brokers to be had this day and contain whole information regarding dosing regimens.
In reaction to becoming matters approximately overuse of antibiotics, the publication comprises guidance on while to not prescribe antimicrobials.
Key positive aspects in nineteenth Edition!
- up to date information about the energy and the extent of facts for all remedy concepts
- New bankruptcy on antibiotic treatment for overweight teenagers
- New bankruptcy on antimicrobial prophylaxis and prevention of symptomatic an infection
- contains therapy of parasitic infections and tropical drugs.
- up to date anti-infective drug directory, entire with formulations and dosages.
- Balanced details on safeguard, efficacy and tolerability with facts on expenses and availability of gear
Read Online or Download 2012-2013 Nelson's Pediatric Antimicrobial Therapy, 19th Edition PDF
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Extra resources for 2012-2013 Nelson's Pediatric Antimicrobial Therapy, 19th Edition
26 — Chapter 5. Antimicrobial Therapy for Newborns A. Recommended Therapy for Selected Newborn Conditions (cont) Ceftazidime IV, IM AND tobramycin IV, IM (AIII) Meropenem, cefepime, OR AND tobramycin are suitable alternatives (AIII). Pip/tazo should not be used for CNS infection. – S aureus16,75–77,86,87 MSSA: oxacillin/nafcillin IV, IM, or cefazolin IV, IM (AII) MRSA: vancomycin IV (AIII) Alternatives for MRSA: clindamycin, linezolid – Staphylococcus epidermidis (or any coagulase-negative staphylococci) Vancomycin IV (AIII) If organism susceptible and infection not severe, oxacillin/nafcillin or cefazolin are alternatives for methicillin-susceptible strains.
EYE INFECTIONS Conjunctivitis, herpetic57–59 Trifluridine 1% ophth soln OR acyclovir 3% ophth ointment (BII) Acyclovir PO (60–80 mg/kg/day div qid) has been effective in limited studies (BIII). Refer to ophthalmologist. Recurrences common; corneal scars may form. Topical steroids for keratitis while using topical antiviral solution. Long-term prophylaxis for suppression of recurrent infection with oral acyclovir 20–25 mg/kg/dose (max 400 mg) PO bid (little long-term safety data in children). Assess for neutropenia on long-term therapy; potential risks must balance potential benefits to vision (BIII).
Ciprofloxacin and levofloxacin are FDA approved for inhalation anthrax (BIII). Bites, animal and human1,15–18 Pasteurella multocida (animal), Eikenella corrodens (human), Staphylococcus species and Streptococcus species Amox/clav 45 mg/kg/day PO div tid (amox/clav 7:1, Consider rabies prophylaxis for animal bites (AI); see Chapter 1, Aminopenicillins) for 5–10 days consider tetanus prophylaxis. (AII); for hospitalized children, use ticar/clav Human bites have a very high rate of infection 200 mg ticarcillin/kg/day div q6h OR ampicillin (do not close open wounds).